CLINICAL AND EPIDEMIOLOGICAL PROFILE AND FACTORS ASSOCIATED WITH THE ADMISSION OF CHILDREN WITH BRONCHIOLITIS TO A PEDIATRIC INTENSIVE CARE UNIT IN THE HINTERLAND OF PARAÍBA
DOI:
https://doi.org/10.63330/sasciencesv6n2-303Keywords:
Acute Viral Bronchiolitis, Clinical-Epidemiological Profile, Intensive Care Unit, Pediatrics, Respiratory Syncytial VirusAbstract
Acute Viral Bronchiolitis (AVB) is a major cause of infant hospitalization and may progress to severe conditions requiring intensive care. This study aimed to analyze the clinical and epidemiological profile and factors associated with the admission of children with AVB to a Pediatric Intensive Care Unit (PICU) in the Sertão region of Paraíba, Brazil. This retrospective, observational, descriptive, and analytical study reviewed medical records of children admitted to a pediatric hospital’s PICU. Sociodemographic, clinical, and epidemiological characteristics, seasonality, and ventilatory support were assessed. Male patients (62.9%) and infants younger than six months (87.1%) predominated. At admission, 40% had SpO₂ below 90%, and tachypnea, dyspnea, and accessory muscle use were frequent. Cough occurred in 78.6% of cases, fever in 32.9%, and apnea in 4.3%. Prematurity was observed in 12.9%, while congenital heart disease was the only comorbidity (1.4%). Most patients (71.4%) came from the Sertão region, with admissions concentrated between February and July. Non-invasive ventilation was the most common respiratory support (72.9%), lasting one to four days in 75% of cases. The findings indicate a predominance of male infants younger than six months with respiratory impairment requiring ventilatory support. These results characterize admissions to the studied unit and may support care planning and healthcare service organization for children with AVB in the region.
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AL SHIBLI, A. et al. Epidemiology of Bronchiolitis in Hospitalized Infants at Tawam Hospital, Al Ain, United Arab Emirates. The Open Respiratory Medicine Journal, v. 15, p. 7–13, 2021. DOI: https://doi.org/10.2174/1874306402115010007.
ANDREOLIO, C. et al. Airway resistance and respiratory compliance in children with acute viral bronchiolitis requiring mechanical ventilation support. Indian Journal of Critical Care Medicine, v. 25, p. 88-93, 2021. DOI: https://doi.org/10.5005/jp-journals-10071-23594.
ANGURANA, S. et al. Clinico-virological profile, intensive care needs, and outcome of infants with acute viral bronchiolitis: a prospective observational study. Indian Journal of Critical Care Medicine, v. 25, p. 1301-1307, 2021. DOI: https://doi.org/10.5005/jp-journals-10071-24016.
ASSERI, A. A. et al. Respiratory syncytial virus: a narrative review of recent updates and advances in epidemiology, pathogenesis, diagnosis, management, and prevention. Journal of Clinical Medicine, v. 14, 2025. DOI: https://doi.org/10.3390/jcm14113880.
BALDASSARRE, M. et al. Hospitalization for bronchiolitis in children ≤1 year of age, Southern Italy, year 2021: need for new preventive strategies? Italian Journal of Pediatrics, v. 49, 2023. DOI: https://doi.org/10.1186/s13052-023-01455-2.
BRASIL. Ministério da Saúde. Bronquiolite. Brasília, DF: Ministério da Saúde, 2025. Disponível em: https://www.gov.br/saude/pt-br/assuntos/saude-de-a-a-z/b/bronquiolite. Acesso em: 25 abr. 2026.
BRASIL. Ministério da Saúde. Nota técnica nº 31/2026: estratégia com nirsevimabe para prevenção do vírus sincicial respiratório (VSR). Brasília: Ministério da Saúde, 2026. Disponível em: https://www.gov.br/saude/pt-br/vacinacao/notas-tecnicas/2026/nota-tecnica-no-31-2026-cgici-dpni-svsa-ms. Acesso em: 25 abr. 2026.
BORLAN, M. L. et al. Australasian Bronchiolitis Guideline: 2025 Update. Journal of Paediatrics and Child Health, v. 61, n. 8, p. 1197–1215, 2025. Disponível em: https://doi.org/10.1111/jpc.70144. Acesso em: 25 abr. 2026.
BULTEN, R. et al. Noninvasive ventilation in pediatric bronchiolitis: variables related to weaning readiness and approach. Canadian Respiratory Journal, v. 2026, e2042835, 2026. DOI: https://doi.org/10.1155/CARJ/2042835.
DALEZ, N. M. et al. Risk factors for respiratory decompensation among healthy infants with bronchiolitis. Hospital Pediatrics, v. 7, n. 9, p. 530-535, 2017. DOI: https://doi.org/10.1542/hpeds.2017-0034.
DALLAGIACOMA, Giulia et al. Risk factors for severe outcomes of respiratory syncytial virus infection in children: a nationwide cohort study in Sweden. The Lancet Regional Health – Europe, v. 58, 101447, 2025. Disponível em: https://doi.org/10.1016/j.lanepe.2025.101447. Acesso em: 25 abr. 2026.
DALZIEL, S. R. et al. Bronchiolitis. The Lancet, v. 400, n. 10349, p. 392-406, 2022. DOI: https://doi.org/10.1016/S0140-6736(22)01016-9.
DE ANDRADE, N. G. A et al. Bronquiolite viral aguda: um panorama completo da definição, epidemiologia, fisiopatologia, sintomas, tratamento e desfecho. Brazilian Journal of Implantology and Health Sciences, v. 6, n. 7, p. 2430-2442, 2024. Disponível em: https://bjihs.emnuvens.com.br/bjihs/article/view/2605. Acesso em: 01 out. 2025.
DE JACOBIS, I. T et al. Sex differences in blood pro-oxidant status and platelet activation in children admitted with respiratory syncytial virus bronchiolitis: a pilot study. Italian Journal of Pediatrics, v. 46, art. 29, 2020. DOI: https://doi.org/10.1186/s13052-020-0792-x.
DE ROSE, D. U. et al. Comparison of three clinical scoring tools for bronchiolitis to predict the need for respiratory support and length of stay in neonates and infants up to three months of age. Frontiers in Pediatrics, v. 11, 2023. DOI: 10.3389/fped.2023.1040354. Disponível em: https://doi.org/10.3389/fped.2023.1040354?utm_source=chatgpt.com.
EKOUBE, C. E. et al. Predictors of prolonged length of hospital stay and in-hospital mortality in patients aged 1-24 months with acute bronchiolitis in Douala, Cameroon. BMC Pediatrics, v. 24, n. 1, art. 150, 2024. DOI: https://doi.org/10.1186/s12887-024-04653-x.
LINS, G. W. et al. Fisioterapia na bronquiolite: levantamento de técnicas respiratórias. Revista JRG de Estudos Acadêmicos, v. 8, n. 19, 2025. Disponível em: https://revistajrg.com/index.php/jrg/article/view/2572. Acesso em: 21 abr. 2026.
LINSSEN, R. S. et al. Burden of respiratory syncytial virus bronchiolitis on the Dutch pediatric intensive care units. European Journal of Pediatrics, v. 180, p. 3141–3149, 2021. DOI: https://doi.org/10.1007/s00431-021-04079-y. Disponível em: Acessar o artigo.
LOPES, C. B. et al. Avanços no tratamento da bronquiolite: do suporte ventilatório à terapia farmacológica. Brazilian Journal of Implantology and Health Sciences, v. 7, n. 3, p. 1522–1531, 2025. DOI: 10.36557/2674-8169.2025v7n3p1522-1531. Disponível em: https://bjihs.emnuvens.com.br/bjihs/article/view/5494. Acesso em: 21 abr. 2026.
LOVEYS, C. et al. Risk factors for severe bronchiolitis in Australian and Aotearoa New Zealand infants: a systematic review. Journal of Paediatrics and Child Health, 2025. DOI: https://doi.org/10.1111/jpc.70165.
MILIĆ, P. et al. Characteristics of Infants Hospitalized with Bronchiolitis at University Hospital of Split Between 2011 and 2015. Paediatria Croatica, v. 61, n. 2, p. 53–58, 2017. DOI: https://doi.org/10.13112/PC.2017.8.
ORGANIZAÇÃO MUNDIAL DA SAÚDE. Vírus sincicial respiratório (VSR). Genebra: OMS, 2025. Disponível em: https://www.who.int/news-room/fact-sheets/detail/respiratory-syncytial-virus-(rsv). Acesso em: 25 abr. 2026.
PARAÍBA. Secretaria de Estado da Saúde. Plano de ação estadual das doenças respiratórias em pediatria da Paraíba. João Pessoa: SES-PB, 2023. Disponível em: https://paraiba.pb.gov.br/diretas/saude/arquivos-1/cib-2023/resolucao-cib-pb-no-115-plano-de-acao-estadual-das-doencas-respiratorias-em-pediatria-da-paraiba-2.pdf. Acesso em: 24 abr. 2026.
PELLETIER, J. H. et al. Respiratory support practices for bronchiolitis in the pediatric intensive care unit. JAMA Network Open, v. 7, n. 5, e2410746, 2024. DOI: https://doi.org/10.1001/jamanetworkopen.2024.10746.
PEREIRA, E. Q. et al. Análise espaço-temporal de hospitalizações por bronquiolite no Brasil: predição de regiões epidêmicas e períodos para imunização contra o vírus sincicial respiratório. Revista Paulista de Pediatria, v. 41, 2023. DOI: https://doi.org/10.1590/1984-0462/2023/41/2021304.
PRADO, S. I.; Novais, M. A. P. Bronquiolite viral aguda no Brasil: características de tempo de permanência e custos hospitalares. Ciência & Saúde Coletiva, v. 30, n. 4, p. e07402023, 2025. Disponível em: https://www.scielosp.org/article/csc/2025.v30n4/e07402023/#. Acesso em: 19 out. 2025.
QUADROS, B. F. et al. Bronquiolite aguda: panorama descritivo das taxas de mortalidade em crianças com idade inferior a 1 ano. Brazilian Journal of Implantology and Health Sciences, v. 6, n. 7, p. 1241–1251, 2024. DOI: 10.36557/2674-8169.2024v6n7p1241-1251. Disponível em: https://bjihs.emnuvens.com.br/bjihs/article/view/2565. Acesso em: 26 abr. 2026.
ROCHA, D. M. C. et al. Efeitos da fisioterapia respiratória em crianças internadas com bronquiolite viral aguda. Revista Brasileira de Qualidade de Vida, v. 16, 2024. DOI: https://doi.org/10.3895/rbqv.v16n0.18389. Acesso em: 25 abr. 2026.
RODRÍGUEZ-FERNÁNDEZ, R. et al. Age and respiratory syncytial virus etiology in clinical outcomes of bronchiolitis. Journal of Allergy and Clinical Immunology: Global, v. 1, p. 91-98, 2022. DOI: https://doi.org/10.1016/j.jacig.2022.05.005.
SANTANA, M. L. S. et al. Perfil epidemiológico de internações por bronquiolite aguda em pacientes menores de 5 anos na Paraíba entre 2016 e 2025: um estudo ecológico. Revista Delos, v. 19, n. 77, e8673, 2026. DOI: 10.55905/Rdelosv19.N77-073.
SANTOS, R. W. F. et al. Prevalence of respiratory viruses in children in Northeast Brazil: the scenario before the COVID-19 pandemic. IJID Regions, v. 14, 2024. DOI: https://doi.org/10.1016/j.ijregi.2024.100499.
SCHELLER, L. L. et al. Clinical features of patients with bronchiolitis prior to the initiation of noninvasive respiratory support. Respiratory Care, v. 70, n. 7, p. 838-846, 2025. DOI: https://doi.org/10.1089/respcare.11922.
SIDDIQUI, M. F. et al. Clinical predictors of severe bronchiolitis and adverse hospital outcomes in children under two years: a retrospective study. Acta Medica International, 2026. DOI: https://doi.org/10.21276/amit.2026.v13.i2.762.
STOLLAR, F. et al. Frequency, timing, risk factors, and outcomes of desaturation in infants with acute bronchiolitis and initially normal oxygen saturation. JAMA Network Open, v. 3, n. 12, e2030905, 2020. DOI: 10.1001/jamanetworkopen.2020.30905. Disponível em: Acessar o artigo.
UUSITUPA, E. et al. Comparison of hospitalization rates and clinical features between boys and girls with respiratory syncytial virus infection. Influenza and Other Respiratory Viruses, v. 20, 2026. DOI: https://doi.org/10.1111/irv.70235.
VAN HASSELT, T. J. et al. Children born preterm admitted to paediatric intensive care for bronchiolitis: a systematic review and meta-analysis. BMC Pediatrics, v. 23, art. 326, 2023. DOI: https://doi.org/10.1186/s12887-023-04150-7.
Xu, Q. et al. Development and external validation of a simple nomogram for predicting apnea in children hospitalized with bronchiolitis. Frontiers in Pediatrics, v. 10, art. 922226, 2022. DOI: https://doi.org/10.3389/fped.2022.922226.
XU, Q. et al. Establishment and validation of a prediction model for apnea on bronchiolitis. Frontiers in Pediatrics, v. 12, e1397750, 2024. DOI: https://doi.org/10.3389/fped.2024.1397750.
ZAR, H. J. New advances in respiratory syncytial virus prevention and treatment. Pediatric Pulmonology, v. 60, supl. 1, p. S120–S122, 2025. Disponível em: https://pubmed.ncbi.nlm.nih.gov/39466029/. Acesso em: 25 abr. 2026.
WORLD HEALTH ORGANIZATION. WHO consolidated guidelines for the management of common childhood illness: management of asthma in children and adolescents and bronchiolitis in infants and young children. Geneva: World Health Organization, 2026. ISBN 978-92-4-012268-0. Disponível em: https://www.who.int/publications/i/item/9789240122680?utm_source=chatgpt.com.
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